351. As a result of injury of tongue a 32-year-old male had a heavy bleeding. The bleeding can be stopped by ligating an artery in the following topographic anatomic region (triangle):
352. A 60-year-old patient has taken a drug to relieve angina pectoris attack; in several minutes pain felt in the breastbone area abated, but it was followed by feeling of vertigo, headache, tinnitus, and hyperemia of face. What drug has he taken?
353. Experimenters irritate the peripheral segment of the intersected sympathetic nerve of an experimental dog. Which of the following changes will be observed?
354. A 46-year-old patient consulted an oculist about drooping of the upper eyelid. On examination he was diagnosed with a brain tumor. The pathological process must have affected the nuclei of the following pair of cranial nerves:
355. A histological preparation of cerebellum transverse section shows large number of multipolar neurons in the grey matter. What morphological feature allows to identify them as multipolar?
356. A connective tissue preparation stained with hematoxylin-eosin shows isogenous cell groups surrounded with basophilic intercellular substance. No fibrous structures detected. What type of connective tissue is it?
357. A patient has temporal bone fracture caused by an accident. What muscle functioning is disrupted?
358. In the process of metabolism human body produces active oxygen forms, including superoxide anion radical O 2 . This anion is inactivated by the following enzyme:
359. A 49-year-old patient has psychotic manifestations in form of psychomotor agitation, auditory and visual hallucinations. What drug is indicated in the described case?
360. A 70-year-old man has developed prosphetic stomatitis. Apart of this he was found to have an evident lesion of mouth corners. Microscopical examination revealed large ovoid gram-positive cells. What microorganisms are most likely to be the leading etiological agent of such a lesion?
361. Certain infections caused by bacteria are treated with sulphanilamides that block the synthesis of bacterial growth factor. What is the mechanism of these drugs action?
362. Ionizing radiation or vitamin E deficiency may increase the permeability of lysosome membranes. What consequences may arise from this pathology?
363. A patient complains of pain in the thorax during breathing, dyspnea, restriction of coughing movements, hiccup. What respiratory muscles are affected?
364. Microscopy of dental plaque revealed unicellular organisms. Their cytoplasm had two distinct layers, barely visible core, wide pseudopodia. The patient is most likely to have:
365. Examination of a 23-year-old patient reveals that when his tongue is protruded, its tip deviates to the side. This is caused by the dysfunction of the following tongue muscle:
366. Novocaine acts as an anesthetic by making nerve fibers unable to conduct stimulation. What mechanism of action regarding membrane’s permeability to ions does this drug have?
367. A patient has an inflammation in the pterygopalatine fossa. The infection has spread to the nasal cavity. What anatomic structure has the infection penetrated through?
368. A 50-year-old patient has been referred for treatment of neck lymphadenitis. His individual penicillin sensitivity was tested. In 30 seconds full-body fever raised in the patient and his arterial blood pressure dropped to 0 mm Hg, followed by cardiac arrest. Resuscitation was unsuccessful. Autopsy revealed acute venous hyperemia of viscera. Histological study revealed mast cells (tissue basocytes) degranulation in the skin (at the area of injections), myocardium and lungs. What kind of hypersensitivity reaction occurred in patient?
369. A female patient with toxemia of pregnancy has hypersalivation resulting in a daily loss of 3-4 liters of saliva. What disorder of water-salt metabolism occurs in such cases?
370. Examination of a chemical plant worker who had had a poisoning revealed an increase in total bilirubin concentration at the expense of indirect fraction. Feces and urine are characterized by high stercobilin concentration. The level of direct bilirubin in blood plasma is normal. What type of jaundice is the case?
371. A patient has the pronounced pain syndrome induced by neuralgia. What drug from the group of nonsteroidal antiinflammatory drugs will reduce pain sensitivity?
372. Tooth temperature increases during its preparation due to dental borer friction, which may cause painful sensations. What is the threshold of teeth thermal sensitivity?
373. A 49-year-old male patient with myocardial infarction has been admitted to the cardiology department. What changes in the peripheral blood cells are induced by the necrotic changes in the myocardium?
374. A patient has some vesicles on the mucous membrane of the oral cavity, lips and nose. A dentist suspected vesicular stomatitis. What analysis will allow to confirm the diagnosis?
375. A patient complains of feeling of pain in his upper jaw and teeth. Physical examinations reveals painful feeling when supraorbital incisure area is pressed. What nerve is damaged?
376. A 31-year-old patient has deep caries of the fifth maxillary tooth on the right. Acute purulent inflammation in the region of the tooth apex has developed. There is marked edema with isolated neutrophils in the perifocal tissues and soft tissues of cheek and palate. Diagnose the pathologic process in the soft tissues of cheek and palate:
377. After the extraction of the lower first premolar the patient had dentoalveolar haemorrhage. What artery did the bleeding occur from?
378. Orthodontic treatment of a child proved to be ineffective due to the chronic mouth breathing since the nasal breathing is impaired. This is caused by the hypertrophy of the following tonsils:
379. A 35-year-old patient had a cerebral injury that caused a hemorrhage in the region of the medial surface of the frontal gyrus and cingulate gyrus. What artery supplies blood to the area of the hemorrhage localization?
380. A 32-year-old patient has B 2 hypovitaminosis. The specific symptoms such as epithelial, mucosal, skin and corneal lesions are most likely to be caused by the deficiency of: hypovitaminosis. The specific symptoms such as epithelial, mucosal, skin and corneal lesions are most likely to be caused by the deficiency of:
381. To perform a scheduled surgery on the upper jaw, a surgeon decided to apply ataralgesia. What medications are used for this manipulation?
382. A patient in a collaptoid state has been given an injection of mesatonum for the correction of blood pressure. What is the mechanism of this drug action?
383. An injury to the occipital region resulted in apnoea. What could be the immediate cause of apnoea?
384. Microscopic examination of the biopsy sample taken from a deformed upper jaw bone revealed areas of bone resorption and replacement of bone tissue by randomly arranged bundles of mature collagen fibers with spindle and stellate cells; primitive structure of trabeculae; myxomatous foci. What is the most likely diagnosis?
385. A 60-year-old man consulted a doctor about an onset of chest pain. In blood serum analysis showed a significant increase in the activity of the following enzymes: creatine kinase and its MBisoform, aspartate aminotransferase. These changes indicate the development of the pathological process in the following tissues:
386. Curarelike substances (dithylinum) make it impossible for skeletal muscles to contract because they block:
387. A histological preparation of multirooted tooth reveals polygonal cells with processes in the root bifurcation area. What cells and what dental tissues are characterised by these morphologic features?
388. Activation of certain hemostasis system factors is done through calcium ions attachment. What structural component allows this attachment?
389. When examining a child the dentist found the deposit on both tonsils and suspected atypical form of diphtheria. A smear was taken, and after the nutrient media inoculation the toxicity of the isolated pure culture was determined. What reaction was used to determine the toxigenicity of the isolated strain of diphtheria bacillus?
390. Proliferation of connective tissue in the parenchyma of liver (fibrosis) caused by chronic diseases is typically accompanied by an impairment of blood circulation in the classic lobules. What is the direction of blood flow in these lobules?
391. A 36-year-old injured has an occipital bone injury causing damage to the sigmoid sinus. What part of the bone is damaged?
392. In some areas of South Africa many people have sickle cell disease characterized by red blood cells that assume an abnormal sickle shape due to the substitution of glutamic acid for valine in the hemoglobin molecule. What is the cause of this disease?
393. Calcification of the intercellular substance of bone tissue is accompanied by the deposition of hydroxyapatite crystals along the collagen fibers. This process requires the presence of alkaline phosphatase in the intercellularsubstance. What cell produces this enzyme?
394. A young man has the following symptoms: purulent acne on the face; wrinkled, hyperemic skin; eyebrows and eyelashes are falling out. A doctor has made a diagnosis of demodicosis (demodectic mange). What preventive measures can be recommended?
395. To prevent the seasonal influenza epidemics in the city hospitals, sanitary epidemic station gave orders to immunize health care workers. Which of the following preparations should be used for immunization?
396. In order to eliminate occupational risks dental workers underwent vaccination. The vaccine should protect them from a viral infection, whose pathogen may be found in blood of dental patients who had had this infection or who are its chronic carriers. What vaccine was used?
397. A histological specimen represents an organ made up of skeletal crossstriated muscle tissue. The organ has cutaneous, intermediate, and mucosal sections. The skin of the organ is stratified squamous keratinizing epithelium passing into nonkeratinizing epithelium in the mucosal section. Specify this organ:
398. Experimental studies revealed steroid hormones to have an effect on proteosynthesis. They influence synthesis of the following substances:
399. A 34-year-old patient underwent a tooth extraction. The tooth crown was of diamond shape and had four tubercles on the masticatory surface, the tooth had three roots. What tooth was extracted?
400. Activation of free radical processes is a universal mechanism that triggers cell death. What inhibitors of this process should be administered as a part of therapeutic interventions intended for the treatment of generalized periodontitis?
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