301. A patient has air embolism as a result of a skin injury in the middle portion of the sternocleidomastoid muscle. Which cervical vein was injured?
302. A 36-year-old male patient has malabsorption of sodium ions from the intestinal lumen into blood. At the same time, absorption of the following substances REMAINS UNCHANGED:
303. Microscopy of a smear taken from the film that appeared on the peptone water 6 hours after seeding and culturing of a fecal sample in a thermostat revealed mobile gram-negative bacteria curved in form of a comma that didn’t make sporesor capsules. What microorganisms were revealed?
304. A patient is diagnosed with pancreatic diabetes with associated hyperglycemia. Glycemia rate can be assessed retrospectively (4-8 weeks prior to examination) by measuring concentration of the following blood plasma protein:
305. A 23-year-old patient consulted an oculist about vision impairment. Visual activity was corrected by means of lenticular lenses. Specify the type of dysfunction of the visual analyzer in this patient:
306. An attack of tachycardia was stopped by pressing on the eyeballs. Which of the following reflexes underlies this phenomenon?
307. A patient complains of an increased sensitivity of the posterior third of his tongue as well as of a gustatory disturbance in this region. What nerve is damaged?
308. Children often have laboured nasal breathing which is caused by overdevelopment of lymphoid tissue of the pharyngeal mucous membrane. This phenomenon may cause enlargement of the following tonsils:
309. A 42-year-old female patient consulted a doctor about pain in the knee joints. Objectively there is swelling, redness, hyperthermia in the region of these joints. Laboratory testing revealed positive acute phase reactants. What drugs should be used to treat this patient?
310. A 30-year-old patient with pneumonia has been administered a 3-day course of an antibiotic from the group of azalides that has bactericidal effect, prolonged action, the ability to bind to phagocytic cells and accumulate in the infection foci. What drug has been administered?
311. Enamel hypoplasia is caused by a dominant gene localized in the X chromosome. Mother has a normal enamel, and father has enamel hypoplasia. Which of children will have this anomaly?
312. A patient with hypoparathyreosis has multiple carious lesions of teeth. This pathology is caused by insufficiency of the following hormone:
313. As a result of an injury the patient is unable to move his tongue forward and downward. Which of the following muscles is damaged?
314. A patient has a systemic inflammatory lesion of connective tissue. Which antiinflammatory drug will reduce all the inflammatory phases?
315. A patient has been hospitalised with provisional diagnosis of hepatitis B. To make a diagnosis, serological reaction is used, which is based on antigen reacting with antibody chemically bound with peroxidase or alkaline phosphatase. What is the name of this serological reaction?
316. A 29-year-old patient with bacterial pneumonia has been administered penicillin. What is the mechanism of its antimicrobial action?
317. A patient with inflammation of tongue mucosa (glossitis) complains of taste sensitivity disorder in the two anterior thirds of the tongue. This is caused by the lesion of the following nerve:
318. A patient has oliguria caused by acute renal failure. What daily amount of urine corresponds with this symptom?
319. Following the tooth extraction for acute pulpitis complicated by purulent periodontitis a patient developed osteomyelitis of mandible. 10 days later the patient died with symptoms of severe intoxication. Autopsy revealed a 2x2 cm large abscess of the right frontal lobe of brain, bilateral abscessed pneumonia, myeloid hyperplasia of spleen. What is the most likely diagnosis?
320. For the treatment of periostitis a 35-year-old patient should be administered an antibiotic with a high ability to penetrate into the bone tissue. Specify this drug:
321. A patient with pituitary tumor complains of increased daily diuresis (polyuria). Glucose concentration in blood plasma equals 4,8 mmol/l. What hormone can be the cause of this if its secretion is disturbed?
322. A patient with acute retention of urine has been brought to an admission room. During examination a doctorfound out that the patient has urethral obturation caused by pathology of the surrounding organ. Name this organ.
323. Diphtheria exotoxin had been treated with 0,3-0,4% formalin and kept in a thermostat for 30 days at a temperature of 4 0 oC. What preparation was obtained as a result of these manipulation s ?C. What preparation was obtained as a result of these manipulations?
324. Having recovered from angina a 23-year-old patient developed urinary syndrome (hematuria, proteinuria, leukocyturia). Study of the puncture biopsy of a kidney revealed manifestations of intracapillary proliferative glomerulonephritis, and electron microscopy revealed large subepithelial deposits. What is the pathogenesis of this disease?
325. During auscultation a 26-year-old patient was asked to breathe deep. After 10 breaths the patient lost consciousness, which is associated with the development of the following condition:
326. A 60-year-old patient with a history of bronchial asthma has had several attacks during the day. What is the optimal drug to be used for their prevention?
327. After using a toothpaste a 27year-old patient has developed Quincke’s edema. Administer a drug from the group of histamine H1-receptor antagonists for the treatment of this condition:
328. Phenylketonuria is a disease caused by a recessive gene that is localized in the autosome. The parents are heterozygous for this gene. They already have two sons with phenylketonuria and one healthy daughter. What is the probability that their fourth child will have the disease too?
329. Platelet adhesion at the site of vascular injury is of great importance for the mechanisms of primary hemostasis. Which factor plays a major part in this process?
330. A 35-year-old patient complains of pain in the upper jaw, bleeding, a slight loosening of teeth. He has been diagnosed with periodontitis. What is a typical pathological process in this case?
331. Examination of a teenager revealed a congenital heart disease, namely the functioning of Botallo’s duct. In the prenatal period of development this duct connects the following organs:
332. A patient complains of toothache. On examination he has been diagnosed with pulpitis. Which factor played a main pathogenic role in the development of pain syndrome in this case?
333. Following treatment with a highlyefficient anti-tuberculosis drug a 48-yearold female developed optic nerve neuritis, memory impairment, cramps. Which of these anti-TB drugs had the patient taken?
334. In Western Europe nearly half of all congenital malformations occur in the children conceived in the period when pesticides were used extensively in the region. Those congenital conditions result from the following influence:
335. A patient from Prykarpattia (at the foot of the Carpathian mountains) with endemic goiter consulted a doctor about suppuration of gingival angles and loosening of teeth. What is a major factor of periodontitis development in this case?
336. A patient with rheumatoid arthritis has been given hydrocortisone for a long time. He has developed hyperglycemia, polyuria, glycosuria, thirst. These complications of treatment result from the activation of the following process:
337. After restoration of maxllary incisors with artificial crowns a 44-year-old female was found to have a brownish overgrowth in form of a node of 15 mm in diameter. Histological study revealed that under the stratified squamous epithelium of gingiva there was a connective tissue mass with numerous sinusoidal vessels, ovalshaped mononuclear cells forming osteoid substance, and polynuclear giant cells that destroyed the alveolar ridge of the upper jaw. What is the most likely diagnosis?
338. When examining the child’s oral cavity, a dentist has noticed growth of the child’s first permanent canines. How old is the child?
339. Human X chromosome contains a dominant gene that is reponsible for normal blood clotting. An autosomal dominant gene plays a similar role. Lack of any of these genes leads to the coagulation disorder. The form of interaction between these genes is called:
340. Autopsy of a young man revealed some lung cavities with inner walls made up of granulation tissue with varying degrees of maturity; pronounced pneumosclerosis and bronchiectasis. Some cavities had caseation areas. What is your presumptive diagnosis?
341. After severe viral hepatitis a 4-year-old boy presents with vomiting, occasional loss of consciousness, convulsions. Blood test revealed hyperammoniemia. Such condition is caused by a disorder of the following biochemical hepatic process:
342. A female who had been continuously taking antibiotics for an intestinal infection developed a complication manifested by inflammation of the oral mucosa and white deposit. Bacteriological study of the deposit samples revealed yeast fungi Candida albicans. Which of the following medications is indicated for the treatment of this complication?
343. An autopsy of the body of a 56-yearold man, who was suffering from secondary tuberculosis, has revealed large areas of sclerosis in the I-II segments of the right lung. Tissue surrounding affected areas is pale, soft, convex; crunches when cut; does not recede. Specify the changes occuring in the tissues surrounding sclerosis focus.
344. After an infectious disease a 21year-old patient exhibits the inability to rotate his head in the direction opposite to the affected region. What nerve has been damaged?
345. Following a cold, a patient developed numbness on the right side of his face. Examination revealed a disturbance of pain and temperature sensitivity on the right side of the face. What nerve is damaged?
346. Cationic glycoproteins are the major components of parotid saliva. What amino acids are responsible for their positive charge?
347. During gastrulation the Hensen’s node remained underdeveloped in the embryo. Which axial organ will slow down its development?
348. A patient has been prescribed the salt-free diet. What changes to the salt taste sensitivity threshold should be expected?
349. A 50-year-old woman with myocardial infarction has been delivered to the intensive care unit. Which enzyme’s activity will be most increased during the first two days?
350. Throughout a year a 37-year-old woman periodically got infectious diseases of bacterial origin, their course was extremely lingering, remissions were short. Examination revealed low level of major classes of immunoglobulins. The direct cause of this phenomenon may be the following cell dysfunction:
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