фарма англ 3

Додано: 7 січня
Предмет: Французька мова, 11 клас
32 запитання
Запитання 1

Urination in the human is decreased by

варіанти відповідей

Muscarinic agonists

Muscarinic antagonists

AChase inhibitors

Nicotinic agonists

Spider venom

Запитання 2

A 5-year-old child becomes ill while visiting relatives who have a farm in Arkansas. His symptoms include severe abdominal cramps with vomiting and diarrhea and profuse lacrimation and salivation. Pupillary constriction is marked. The most likely cause is exposure to

варіанти відповідей

Herbicides

Antifreeze

Lead-based paint

Insecticides

Rat poison

Запитання 3

The activation of muscarinic receptors in bronchiolar smooth muscle is associated with

варіанти відповідей

Activation of adenylyl cyclase

Decrease in cAMP formation mediated by G-proteins

Increase in IP3 and DAG

Inhibition of protein kinase C

Opening of Na+/K+ cation channels

Запитання 4

Ganglion blocking agents are of little clinical value today but they are important drugs to know for solving cardiovascular drug problems because they can block 

варіанти відповідей

All muscarinic receptors

All nicotinic receptors

All autonomic reflexes

The direct actions of drugs on blood vessels

The direct actions of drugs on the heart

Запитання 5

An 11-year-old boy was brought to the ER by some of his friends because he “started going crazy” after eating seeds from a plant while “trying to get high.” The boy was incoherent; his skin was hot and dry. His pupils were dilated and unresponsive to light. Blood pressure was 180/105, pulse 150, and rectal temp 40°C. The presumptive diagnosis was drug toxicity due to the ingestion of a compound similar to

варіанти відповідей

Cannabis

Digoxin

Mescaline

Phencyclidine

Scopolamine

Запитання 6

Thermoregulatory sweat glands in the body utilize what type of pathway?

варіанти відповідей

Cholinergic nerves and muscarinic receptors

Adrenergic nerves and alpha-1 receptors

Adrenergic nerves and beta-2 receptors

Cholinergic nerves and NM receptors

Neurohumorally-released epinephrine

Запитання 7

Following pretreatment with a muscarinic receptor blocking agent, the IV administration of norepinephrine is likely to result in

варіанти відповідей

↑ HR and ↑ BP

↑ HR and ↓ BP

↓ HR and ↓ BP

↓ HR and ↑ BP

no effect on HR, but ↑ BP

Запитання 8

A colleague with myasthenia gravis wants you to assist him to the ER because he is experiencing muscle weakness and has found it difficult to titrate his drug dosage because he has had the “flu.” You note that he has a slight temperature, shallow respirations, and a gray-blue skin pallor. What would be the most appropriate drug to give to your colleague at this time?

варіанти відповідей

Albuterol

Edrophonium

Propranolol

Physostigmine

Scopolamine

Запитання 9

Neostigmine differs from pilocarpine in having effects on

варіанти відповідей

Bladder tone

Bowel motility

Heart rate

Salivary glands

Skeletal muscle

Запитання 10

A 37-year-old woman has blurred, double vision 8 hours after eating home-preserved peppers. Six hours later, she has dysphagia, dry mouth and eyes, progressive weakness of the arms and legs, and urinary retention. She is awake and alert. Which of the following is the most likely mechanism of these adverse effects?

варіанти відповідей

Antagonism of muscarinic receptors

Antagonism of nicotinic receptors

Inhibition of acetylcholine release

Inhibition of cholinesterase activity

Inhibition of G proteins

Запитання 11

The first-aid center has received a victim of a traffic accident diagnosed with closed displaced fracture of the middle third of the thigh. For repositioning of the bone fragments the patient received 10 mL of 2% Dithylinum solution intravenously, which resulted in the prolonged period of apnoea and muscle relaxation. What enzyme is deficient, resulting in such pharmacogenetic enzymopathy?

варіанти відповідей

Pseudocholinesterase

Uridine diphosphate glucuronyltransferase

Glucose 6-phosphate dehydrogenase

Methemoglobin reductase

N-acetyltransferase

Запитання 12

During gastric resection the patient received mixed anesthesia with Tubocurarin chloride muscle relaxant; to restore spontaneous respiration the patient received Proserin. What pharmacological group does this drug belong to?

варіанти відповідей

Cholinesterase inhibitors

Angiotensin-converting-enzyme inhibitors

Calcium channel blockers

Muscarinic antagonists

Muscarinic agonists

Запитання 13

A 47-year-old man developed intestinal colic against the back ground of essential hypertension. In this situation it would be most efficient to arrest the colic by administering drugs of the following group: 

варіанти відповідей

Myotropic antispasmodics

Anticholinesterase agents

Sympathomimetics

M-cholinomimetics

Adrenomimetics

Запитання 14

A 36-year-old patient has been administered a depolarizing muscle relaxant during a surgery. Name this drug:

варіанти відповідей

Dithylinum 

Proserin

Pipecuronium bromide (Arduan) 

Diazepam

Aminazine

Запитання 15

A patient after disrupted cerebral circulation has developed paralysis. Choose the anticholinesterase drug to be prescribed in this case:

варіанти відповідей

Proserin 

Cordiamin

Aceclidine

Methacin

Hexamethonium (Benzohexonium) 

Запитання 16

A patient was prescribed atropine sulfate to treat intestinal colic. What concomitant disease can be a contraindication for this drug? 

варіанти відповідей

Glaucoma 

Bronchial asthma 

Sinus bradycardia

Hypotension

Vertigo 

Запитання 17

At the 2-3 day after the gastric resection the patient’s intestinal peristalsis failed to restore. What should the patient be prescribed to stimulate the function of his gastrointestinal tract? 

варіанти відповідей

Proserin

Platyphyllin

Cyclodol (Trihexyphenidyl)

Atropine

Dithyline (Suxamethonium chloride)

Запитання 18

The first-aid center has received a victim of a traffic accident diagnosed with closed displaced fracture of the middle third of the thigh. For repositioning of bone fragments the patient received 10ml of 2% dithylinum solution intravenously, which resulted in prolonged period of apnoea and muscle relaxation.What enzyme is deficient, resulting in such pharmacogenetic enzymopathy?

варіанти відповідей

Pseudocholinesterase

Uridine diphosphate glucuronyltransferase

Glucose6-phosphate dehydrogenase

Methemoglobinreductase

N-acetyltransferase 

Запитання 19

After a nephrectomy the patient developed enteroparesis. What cholinergic agent with anticholinesterase action should be prescribed in this case?

варіанти відповідей

Proserin 

Carbacholine

Aceclidine

Pilocarpine

Acetylcholine

Запитання 20

A patient, who has been taking β- adrenergic blockers, developed a bronchial spasm. What group of bronchodilators should be chosen to stop the bronchial spasm?

варіанти відповідей

Myotropic antispasmodics 

β-adrenergic blockers

Indirect adrenergic agonists

Muscarinic cholinomimetic agents

Cholinesterase inhibitors 

Запитання 21

A patient complains of dizziness, thirst, difficult swallowing, and impaire dvision of close objects. Objectively: respiratory rate is increased, pupils are dilated, general agitation, talkativeness, though the speech is indistinct. BP is 110/70 mm Hg, heart rate is 110/min. Given symptoms can indicate overdosage of the following drug: 

варіанти відповідей

Atropine

Morphine

Ephedrine

Aminazine

Caffeine

Запитання 22

A patient has been given atropine sulfate for rapid relief of spastic colon symptoms. The use of this drug is contraindicated during the followng disease:

варіанти відповідей

Glaucoma 

Bronchial asthma

Bradycardia

Hypotension

Gastriculcer 

Запитання 23

Analeptical remedyof reflective type from the H-cholinomimetics group was given to the patient for restoration of breathing after poisoning with carbon monoxide. What medicine was prescribed to the patient?

варіанти відповідей

Atropine sulphate 

Adrenalin hydrochloride 

Mesaton 

Pentamin

Lobeline hydrochloride 

Запитання 24

What drug causes dilation of the pupil and paralysis of accommodation when instilled in the eyes?

варіанти відповідей

Prozerin (Nestigmine)

Pilocarpine hydrochloride

Atropine sulfate

Galantamine hydrobromide

Furacilin (Nitrofural)

Запитання 25

Tubocurarine chloride was used during dislocation reduction in a patient. Soon the patient developed overdose symptoms. What drug should be used to eliminate these symptoms?

варіанти відповідей

Omeprazole

Furosemide

Prozerin (Neostigmine)

Morphine

Dithylin (Suxamethonium)

Запитання 26

A man was hospitalized with abdominal pain and profuse salivation, sweating, and tears. Examination detects miosis. The day before, he was treating plants with a solution of an insecticidal substance without wearing personal protective equipment. The substance that has caused the poisoning in this case belongs to:

варіанти відповідей

Organochlorine compounds

Copper salts

Nicotinic cholinomimetics

Nitrates

Anticholinesterase agents

Запитання 27

A 48-year-old woman has been diagnosed with Raynaud syndrome (a spasm of peripheral blood vessels) and prescribed an adrenotropiс agent. What group does this drug belong to?

варіанти відповідей

β1-blockers

α-blockers

β2-blockers

β1-adrenergic agonists

α/β-adrenergic agonists

Запитання 28

An ophthalmologist used a 1% Mesaton solution for the diagnostic purpose (pupil dilation for eye-ground examination). What is the cause of mydriasis induced by the drug? 

варіанти відповідей

Activation of α2 adrenoreceptors 

Block of α1 adrenoreceptors 

Activation of β1 adrenoreceptors 

Activation of α1 adrenoreceptors 

Activation of M-cholinoreceptors

Запитання 29

During a surgery with the use of Hygronium the patient had an abrupt fall in blood pressure. Blood pressure can be normalized by the representatives of the following drug group: 

варіанти відповідей

α-adrenergic agonists 

α-blockers 

Ganglionic blockers 

M-cholinergic agents 

N-cholinergic agents

Запитання 30

A patient ill with bronchial asthma didn’t inform his doctor that he had attacks of stenocardia. Doctor administered him a medication, which taking resulted in less frequent attacks of bronchial asthma, but stenocardia attacks became more frequent. What medication was administered?

варіанти відповідей

Isoproterenol (isadrin)

Salbutamol 

Aminophylline 

Cromolyn sodium 

Fenoterol

Запитання 31

A patient with coronary artery disease was admitted to the cardiological department. For stenocardia prevention a drug from the group of β-adrenoceptor blockers was administered. What drug is it?

варіанти відповідей

Atropine sulfate 

Metoprolol 

Morphine hydrochloride 

Oxytocin 

Furosemide

Запитання 32

A 68-year-old patient consults a cardiologist, complaining of high arterial blood pressure, pain in the heart egion, intermittent pulse. Prescribe the β1-adrenoreceptor blocker for the treatment of the described pathology: 

варіанти відповідей

Morphine hydrochloride 

Nootropil 

Fenoterol 

Benzylpenicillin

Metoprolol 

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