medical microbiology

Додано: 13 травня
Предмет:
45 запитань
Запитання 1

Which of the following tests used to diagnose syphilis are non-treponemic serological tests?

варіанти відповідей

Treponema pallidum antigens 

Venereal Diseases Laboratory Test

Absorption test for fluorescent antitreponemic antibodies 

Rapid plasma reagent test

Solid phase immunosorbent assay (ELISA) 

Запитання 2

Which of the following vaccines is used for the specific prevention of hepatitis B virus infection?

варіанти відповідей

Corpuscular vaccine containing heat-inactivated hepatitis B virus. 

Live vaccine containing attenuated hepatitis B virus. 

Subcellular (subunit) vaccine containing purified hepatitis B virus core HBc antigens. 

Subcellular (subunit) vaccine containing purified HBs antigens on the surface of the hepatitis B virus. 

Запитання 3

Which of the following bacterial species is characterized by pairing (diplococci), polysaccharide capsule formation, and growth on chocolate agar?


варіанти відповідей

Neisseria meningitidis 

Streptococcus pyogenes 

Streptococcus pneumoniae 

Haemophilus influenzae b serovaras 

Neisseria gonorrhoeae 

Запитання 4

In which of the following variants are all bacterial species correctly assigned to the respective family?

варіанти відповідей

Streptococcaceae family: S. mutans, S. pneumoniae, S. pyogenes 

Clostridiaceae family: C. botulinum, C. perfringens, C. tetani 

Enterobacteriaceae family: S. enterica, S. sonnei, E. coli 

Enterobacteriaceae family: Y. enterocolitica, C. jejuni, H. pylori 

Запитання 5

Which of the following microorganisms are classified as true human pathogens? 

варіанти відповідей

Aspergillus flavus 

Cryptococcus neoformans 

Trichophyton rubrum 

Entamoeba histolytica 

Candida albicans 

Запитання 6

Which of the following methods is used for the microbiological diagnosis of human immunodeficiency virus infection?

варіанти відповідей

Solid-phase immunosorbent assay (ELISA) for the detection of antiviral antibodies in the blood.

Immunoblot.

Haemagglutination inhibition reaction.

Quantitative real-time reverse transcription-polymerase chain reaction method. 

Haemadsorption reaction. 

Запитання 7

Which of the following measures are used for the specific prevention and control of rabies?

варіанти відповідей

A sub-cell (subunit) vaccine made up of individual rabies virus antigens and used to immunize humans. 

A live vaccine made up of attenuated rabies viruses and used to immunize humans.

Live oral vaccine consisting of attenuated rabies viruses for the immunization of wild animals. 

Immune serum against rabies used for human immunization. 

A corpuscular killed vaccine made up of inactivated rabies viruses and used to immunize humans. 

Запитання 8

What is the basis for the microbiological diagnosis of botulism? 

варіанти відповідей

Detection of exotoxin in the patient's blood serum, food or faeces.

Detection of specific antibodies against the botulinum agent in the blood serum. 

Isolation of a pure culture of the botulism agent from a patient's blood serum. 

Clostridium botulinum spores in a patient's blood serum by microscopy. 

Запитання 9

Prevention of brucellosis is carried out using all the following measures, except : 

варіанти відповідей

pasteurization of dairy products

protective clothing for people working in high-risk work environments 

immunization of animals with the vaccine

human immunization with the vaccine 

Запитання 10

Which variants correctly describe the epidemiology of diseases caused by bacteria belonging to the Enterobacteriaceae family?

варіанти відповідей

Typhoid fever: source of infection - poultry; transmission path - alimony. 

Escherichiosis: source of infection - human; transmission path - air droplet.

Salmonellosis: source of infection - poultry and wild birds; transmission path - alimony. 

Salmonellosis: the source of the infection is a sick person; route of transmission - faecal oral. 

Shigellosis: source of infection - domestic cattle; transmission path - alimony. 

Запитання 11

Which of the following viruses can cause syncytia? 

варіанти відповідей

Herpes simplex virus type 2 

Hepatitis A virus

Human immunodeficiency virus 

Chickenpox virus 

Influenza A virus 

Paragripaviruses 

Запитання 12

Which of the following viruses infect human cells by binding to receptors on sialic acid molecules?

варіанти відповідей

Paragripaviruses 

Influenza B virus

Rhinoviruses

Human immunodeficiency virus 

Influenza A virus

Measles virus 

Запитання 13

The tertiary stage of syphilis is characterized by: 

варіанти відповідей

chancroid in the mucous membrane of the genitals

hard anchor in the genital mucosa

syphilis granulomas (gums) in various organs 

disseminated rash with red spots and blisters on the skin 

Запитання 14

Which of the following variants lists all the bacteria that make up the polysaccharide capsule without exception?

варіанти відповідей

Pseudomonas aeruginosa, Haemophilus influenzae b serovars 

Pseudomonas aeruginosa, Yersinia pestis 

Streptococcus pneumoniae, Neisseria meningitidis 

Neisseria gonorrhoeae , Bacillus anthracis 

Запитання 15

hard ticks of the genus Ixodes are: 

варіанти відповідей

tick-borne encephalitis virus vectors 

endemic reversible fever vectors 

epidemic vectors of spotted fever 

endemic spotted fever vectors 

Carriers of Lyme borreliosis 

Запитання 16

Plasma coagulating staphylococci were isolated from the pus in a bacteriological study. Which of the following statements about isolated bacteria are true?

варіанти відповідей

Deoxyribonuclease activity is positive. 

Catalase activity is positive. 

The smear, made from pure culture and stained by the Gram method, shows gram-positive coca- clad coca. 

Mannitol salts in agar form small, S-shaped, yellow colonies surrounded by a zone of hemolysis. 

Fermentes glucose and mannitol only under anaerobic conditions. 

Запитання 17

Which of the following viruses are identified using the reverse transcription-polymerase chain reaction method?

варіанти відповідей

Rotavirus 

Influenza A virus 

Cytomegalovirus

Hepatitis B virus

Tick - borne encephalitis virus 

Hepatitis C virus 

Запитання 18

Which of the following genetic mechanisms causes pandemic influenza A virus antigen shift (shift)?

варіанти відповідей

Point mutations in influenza A virus genes. 

Transduction between different influenza A viruses.

Conjugation between different influenza A viruses.

Gene exchange (rearrangement) between different influenza A viruses. 

Запитання 19

What is the basis for early microbiological diagnosis of typhoid fever? 

варіанти відповідей

Blood culture and Vidal's reaction. 

Blood crop.

Stool crop.

Vidal's reaction. 

Fecal culture and Vidal's reaction. 

Запитання 20

Which of the following statements about the properties of the legionnaires' disease agent are correct?

варіанти відповідей

Legionella pneumophila is a gram-negative bacterium that forms capsules but does not form spores. 

Sheep blood agar is used to cultivate the legionnaires' disease agent. 

Legionella pneumophila are gram-negative bacteria that do not form capsules and spores. 

The virulence of the legionellosis agent is associated with the inhibition of phagolysosome formation. 

Specially formulated nutrient media are used to cultivate the legionnaires' disease agent. 

Запитання 21

Which of the following statements about bacterial exotoxins are correct? 

варіанти відповідей

Streptococcus pyogenes is highly immunogenic and streptolysin-S is not immunogenic. 

Clostridium botulinum interferes with the release of glycine at synapses. 

Bacillus anthracis is not immunogenic, but is important for the association of edematous or lethal factors with exotoxin formation. 

Clostridium tetani interferes with the release of gamma-aminobutyric acid at synapses. 

Cotnebacterium diphtheriae exotoxin causes cell death by inhibiting protein synthesis in ribosomes. 

Запитання 22

Which of the following statements about Rickettsia prowazekii are correct?

варіанти відповідей

R. prowazekii vectors are tree and dog mites. 

R. prowazekii causes epidemic spotted fever. 

R. prowazekii causes endemic spotted typhoid. 

R. prowazekii is the lice of the human body. 

R. prowazekii bacteria have low levels of peptidoglycans in the wall and are therefore not Gram- stained. 

R. prowazekii infects vascular endothelial cells and causes vasculitis. 

Запитання 23

Which of the following viruses can be detected by a haemagglutination reaction? 

варіанти відповідей

Influenza A virus 

Cytomegalovirus 

Measles virus 

Influenza B virus 

Paragripaviruses 

Hepatitis B virus 

Запитання 24

Which of the following vaccines is used for the specific prevention of infections caused by Haemophilus influenzae b serovar?


варіанти відповідей

Polyvalent polysaccharide vaccine 

Polysaccharide conjugated to protein vaccine 

Тoxoid

Inactivated, corpuscular vaccine

Live, attenuated vaccine 

Запитання 25

Which of the following vaccines are used for the specific prevention of polio? 

варіанти відповідей

Subcellular (subunit) vaccine consisting of individual antigens of 3 serovar polio viruses. 

A corpuscular killed vaccine consisting of inactivated 3 serovar polio viruses.

Live oral vaccine consisting of attenuated 3 serovar poliomyelitis viruses.

Toxoid. 

Запитання 26

Which of the following bacterial species has the following characteristics: three biovars are isolated by glycerol degradation and nitrate reduction, bipolar staining, and formation of R-shaped colonies on blood agar?

варіанти відповідей

Brucella melitensis 

Vibrio cholerae 

Corynebacterium diphtheriae 

Francisella tularensis 

Yersinia pestis 

Запитання 27

Which of the following test methods are used to determine the toxicity of the diphtheria agent?

варіанти відповідей

Culturing of the diphtheria agent on cysteine tellurite blood agar. 

MALDI-TOF protein mass spectrometry method. 

Polymerase chain reaction method.

Elek immunodiffusion test. 

Запитання 28

Which of the following types of bacteria cause food poisoning that occurs only through intoxication of the body?

варіанти відповідей

Staphylococcus aureus 

Salmonella Typhimurium 

Clostridium botulinum 

Listeria monocytogenes 

Campylobacter jejuni 

Запитання 29

In which of the following cells does the Epstein-Barr virus cause latent infection? 

варіанти відповідей

In neurons

T lymphocytes 

In epithelial cells 

B in lymphocytes 

Запитання 30

Which of the following statements about the properties of Mycobacterium tuberculosis are correct?

варіанти відповідей

Levenstein-Jansen agar forms R-shaped colonies with a yellow color. 

The wall contains peptidoglycans.

The wall contains mycolic acids and arabinogalactans. 

Levenstein-Jansen agar forms yellow colonies with a yellow color. 

The wall contains lipopolysaccharides. 

Запитання 31

Which of the following viruses causes infectious mononucleosis and a triad of clinical symptoms of lymphadenopathy, splenomegaly, and exudative pharyngitis? 

варіанти відповідей

Epstein-Barr virus 

Hepatitis B virus 

Influenza A virus 

Cytomegalovirus 

Chickenpox virus 

Запитання 32

Which of the following bacterial toxins activate adenylate cyclase? 

варіанти відповідей

Enterotoxigenic Escherichia coli produces a thermolabile enterotoxin 

Exotoxin A produced by Pseudomonas aeruginosa

Pertussis toxin is produced by Bordetella pertussis

Tracheal cytotoxin is produced by Bordetella pertussis 

Enterotoxigenic Escherichia coli produces a thermostable enterotoxin 

is produced by Vibrio cholerae 

Bacillus anthracis toxin composed of a protective antigen and an edematous factor 

Запитання 33

Which of the following bacterial species is characterized by motility and a positive oxidase reaction?

варіанти відповідей

Yersinia enterocolitica 

Vibrio cholerae

Yersinia pseudotuberculosis 

Salmonella Typhi 

Salmonella Typhimurium 

Запитання 34

Which of the following diseases is associated with erythogenic toxins produced by Streptococcus pyogenes ? 

варіанти відповідей

Pyoderma

Scarlet fever

Rose

Burnt skin syndrome 

Osteomyelitis 

Запитання 35

Which of the following pathogens can be transmitted both by transplacental route and by sexual contact?

варіанти відповідей

Cytomegalovirus 

Treponema pallidum 

Chlamydia trachomatis 

Epstein-Barr virus

Human immunodeficiency virus 

Toxoplasma gondii 

Запитання 36

Which of the following statements about the properties of Pseudomonas aeruginosa are correct?

варіанти відповідей

P. aeruginosa bacteria produce protein capsules made up of glutamic acid. 

P. aeruginosa is a mobile, gram-positive, rod-shaped bacterium. 

P. aeruginosa is a mobile, gram-negative, rod-shaped bacterium.

P. aeruginosa bacteria produce polysaccharide capsules composed of alginate.

P. aeruginosa bacteria produce pioverdin, which gives the colonies a yellowish-green tinge. 

P. aeruginosa bacteria form biofilms. 

Запитання 37

Which of the following statements about Chlamydia trachomatis are correct? 

варіанти відповідей

C. trachomatis reticular cells are infectious. 

C. trachomatis inhibits phagolysosome formation.

C. trachomatis causes venous lymphogranulomatosis.

C. trachomatis can infect macrophages.

elemental cells of C. trachomatis are metabolically active. 

C. trachomatis in the test substance. 

Запитання 38

In which of the following cells does the chickenpox virus cause latent infection? 

варіанти відповідей

In neurons

T lymphocytes

B lymphocytes 

In epithelial cells 

Запитання 39

Which of the following statements about the properties of the listeriosis agent are correct?

варіанти відповідей

Listeria monocytogenes are optional anaerobic bacteria that can grow at ambient temperatures of 4 ° C. 

Listeria monocytogenes are agile, gram-positive, rod-shaped bacteria.

Listeria monocytogenes are anaerobic bacteria that can grow at ambient temperatures of 37 ° C. 

The virulence of the listeriosis agent is associated with the production of pore-forming cytolysin and ActA protein. 

Listeria monocytogenes are immobile, gram-negative, rod-shaped bacteria. 

Запитання 40

Which of the following statements about "burnt skin" syndrome are true? 

варіанти відповідей

It most commonly occurs in newborns and infants.

Develops due to exfoliative toxins produced by Staphylococcus aureus . 

The causative agent is Streptococcus pyogenes.

Develops due to erythogenic toxins produced by Streptococcus pyogenes . 

The causative agent is Staphylococcus aureus

Запитання 41

What is Vidal's reaction used for? 

варіанти відповідей

Differentiate Salmonella Typhi infection from Salmonella Paratyphi A and B infections. 

Vidal's reaction is used as a serological test method to diagnose salmonellosis. 

Vidalia reaction is used as a serological test method to diagnose typhoid fever.

Vidal's reaction is used as a serological test method to diagnose shigellosis. 

Запитання 42

Which of the following viruses are able to integrate their genetic material into the genome of infected cells, causing latent infection?

варіанти відповідей

Influenza A virus 

Hepatitis B virus

Human immunodeficiency virus 

Chickenpox virus

Hepatitis D virus 

Cytomegalovirus 

Запитання 43

Which of the following hepatitis viruses is transmitted via the faecal-oral route and the alimentary route?

варіанти відповідей

Hepatitis C virus 

Hepatitis D virus 

Hepatitis B virus 

Hepatitis A virus 

Запитання 44

The genome of coronaviruses, including SARS-CoV-2, consists of: 

варіанти відповідей

A double-stranded DNA molecule.

Single - stranded reverse (-) RNA molecule. 

A single-stranded forward (+) RNA molecule. 

A double-stranded direct (+) RNA molecule. 

Запитання 45

Which of the following bacterial species has the following characteristics: microaerophilic and capnophilic conditions are required for growth, the source of infection is human only, and the route of transmission is faecal-oral?

варіанти відповідей

Helicobacter pylori 

Campylobacter jejuni 

Salmonella Typhimurium 

Shigella dysenteriae 

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