A 4-year-old child has purulent inflammation of the middle ear. The pathological process has spread to the artery that borders the anterior wall of the tympanic cavity. What vessel is involved in the pathological process?
A 38-year-old female patient has been diagnosed with inflammation of the third branch of the trigeminal nerve. This branch exits the skull through the following foramen:
After starting treatment for pulmonary tuberculosis a patient complained about red tears and urine. What drug could cause such changes?
A woman got infected with rubella during pregnancy. The child was born with malformations, namely cleft lip and palate. The child’s genotype is normal. These malformations are a manifestation of:
During anesthesia of the oral mucosa a 37-year-old patient has had anaphylactic reaction (widespread vasodilation, increased vascular permeability with liquid exiting the blood vessels and penetrating in the tissues). What type of hypersensitivity reaction occurred in the patient?
Mother had noticed her 5-year-old child’s urine to become dark in colour. Bile pigments in urine were not detected. The diagnosis of alkaptonuria was made. What pigment is deficient?
Periodontitis induces the development of lipid peroxidation in the periodontal tissues, as well as an increase in malondialdehyde and hydrogen peroxide concentration in the oral cavity. Which of the following enzymes provides antioxidant protection?
It has been revealed that intense physical exercise causes activation of gluconeogenesis in liver of experimantal rats. Which substance is glucose precursor in this case?
A patient with symptoms of acute heart failure, namely pallor, acrocyanosis and rapid shallow breathing, has been delivered to the emergency department. Which of these drugs is indicated in this case?
An electron microphotograph of duodenal epithelium clearly shows a cell with electron-dense granules in the basal pole. What cell is it?
A 47-year-old male patient consulted a dentist about difficult mouth opening (lockjaw). The patient has a history of a stab wound of the lower extremity. What infection can be manifested by these symptoms?
A patient with liver cirrhosis has been given intravenously 500,0 ml of 5% glucose solution along with other drugs. There is a high risk of the following water-electrolytic balance disruption:
A 36-year-old patient consulted an ophthalmologist about eye ache. The examination revealed the erosion of the cornea, that is the lack of superficial and spinous layers of the epithelium. What cells will provide regeneration of the damaged epithelium?
The emergency department admitted a 48-year-old male with a blunt abdominal injury on the right and a suspected rupture of liver. Which of these peritoneal structures can be expected to include blood accumulations?
A 9-year-old child has multiple lesions of the oral mucosa in form of small painful hyperemic sores with a white deposit in the center; enlarged and painful submandibular lymph nodes. Microscopic examination of the affected region revealed a superficial defect covered by fibrin; edematic and hyperemic submucosa with inflammatory infiltration. What is the most likely diagnosis?
Histological study of the bronchial wall and adjacent lung segments revealed sheets and strands of squamous epithelium. The cells have moderately expressed symptoms of atypia: polymorphism, nuclear hyperchromatism, mitoses. In the center of the complex there are concentric pink formations. What is the most likely diagnosis?
A patient consulted a doctor about loss of taste at the root of tongue. The doctor established that this was due to a nerve damage. What nerve was damaged?
A 58-year-old male patient consulted an urologist about acute pain during urination and decreased amount of the excreted urine. Urolithiasis was suspected. The concrements are most likely to be found in the following part of the urethra:
A student who unexpectedly met his girlfriend developed an increase in systemic arterial pressure. This pressure change was caused by the intensified realization of the following reflexes:
A patient has enamel erosion. What vitamin should be administered for its treatment?
A patient presents with dysfunction of shin muscles. He cannot raise his body by standing on tiptoe. Which muscle is affected?
The patient’s examination in a hospital specialised in diseases of nervous system has revealed absence of light-induced miosis. It is caused by damage of the following brain structures:
The surgically excised connective tissue of the deformed mitral valve gives a basophilic reaction when stained with hematoxylin and eosin. When stained with toluidine blue it turns purple (metachromasia). What changes of the connective tissue can be detected by such reactions?
Examination of a patient revealed a hard palate tumor in form of a small dense gray node without clear boundaries. Histological study of the tumor after its removal revealed the following peculiarities: the tumor was constituted by small cubic cells with hyperchromatic nucleus forming alveoli, trabeculae, solid and cribriform structures. The tumor growth could be charactrized as invasive. Specify the tumor:
A physician performs the anterior transverse cervical skin incision for urgent tracheotomy. He should keep in mind the probability of damaging the following vessel:
A histological specimen represents a blood vessel. Its inner tunica is composed of endothelium, subendothelium and internal elastic lamina. The middle tunica is rich in smooth muscle cells. What vessel is characterized by these morphological features?
A 32-year-old patient undergoing dental examination was found to have some rash-like lesions resembling secondary syphilis in the oral cavity. The patient was referred for the serological study with the purpose of diagnosis confirmation. In order to detect antibodies in the serum, living Treponema were used as diagnosticum. What serological test was performed?
In the experiment, an animal had its brain stem cut, which caused a rapid increase of extensor muscle tone (decerebrate rigidity). This condition arose because the muscles were no more under the control of the following brain structure:
A patient has addressed a doctor with complaint of gastric ulcer exacerbation. The following membrane cytoreceptors should be blocked in the course of the patient’s complex therapy:
ECG of a 46-year-old patient shows an increase in the QRS duration. This might be caused by:
Wilson’s disease is a disorder of copper transport which leads to the accumulation of this metal in brain and liver cells. It is associated with a disturbance in the synthesis of the following protein:
A 30-year-old driver complains of allergic rhinitis that usually excerbates in spring. He has been administered an antihistamine drug with a slight sedative effect and 24-hour period of action. Which of the listed drugs has been administered?
A patient has wound abscess. Bacteriological examination of the wound content revealed a gram-negative bacillus which forms semi-transparent mucous colonies of blue-green colour with a pearlescent appearance on the beefextract agar. Culture has a specific odour of violets or jasmine. What type of pathogen was isolated from the patient’s wound?
Histological examination of the grayishpink elastic nodule of 0,3 cm in diameter found by a surgeon at the root of the extracted tooth shows granulation tissue with cords of stratified squamous epithelium. What is the most likely diagnosis?
Monoamine oxidase inhibitors are widely used in clinics as psychopharmacological drugs. They change the level of the following neurotransmitter in the synapses:
X-chromatin test of somatic cells is used for quick diagnostics of hereditary diseases caused by variations of sex chromosomes number. What is the karyotype of a male, whose cells mostly contain one X-chromatin body?
Autopsy of a man who died from intraintestinal hemorrhage revealed necrosis of grouped and solitary follicles, dead tissues imbibed with bile and blood in the ileum; sequestration and rejection of necrotic masses with defect formation in the lower segment of the intestine. Which of the following diagnoses is most likely?
A patient under examination is in a stage of rapid eye movement sleep. This is confirmed by the following waves registered by EEG:
A 58-year-old patient with essential hypertension complains about general health deterioration. She has been administered methyldopa. Specify the mechanism of this drug action:
In course of an experiment researchers stimulate a branch of a sympathetic nerve that innervates heart. What changes in cardiac activity should be registered?
A physician collects the patient’s history of the post-embryonic period of ontogenesis from birth to puberty. In this case we are talking about:
After a thorough examination the patient who had returned from Central Asia to Ukraine was diagnosed with spring-summer encephalitis. Its pathogen might have entered the body through the bite of the following arthropod:
A female woman has been clinically diagnosed with gonorrhea. Which of the following studies can be used to confirm the diagnosis?
A 42-year-old patient with tetanus developed an acute respiratory failure. What type of respiratory failure occurs in this case?
A histological specimen of mandible of an embryo shows a tooth germ with the dental papilla made up of small stellate basophilic cells. What tissue forms this part of the tooth germ?
Tooth extraction in a patient with chronic persistent hepatitis was complicated by a prolonged bleeding. What is the cause of hemorrhagic syndrome?
Patients with erythropoietic porphyria (Gunther’s disease ) have teeth that fluoresce red on exposure to ultraviolet light; photosensitive skin; red urine. This disease is associated with the lack of the following enzyme:
As a result of treatment of viral RNA with nitrous acid, UCA triplet mutated to UGA triplet. What kind of mutation occurred?
A 26-year-old woman at 40 weeks’ gestation was admitted to the maternity ward. Examination revealed that the cervix was open, but uterine contractions were absent. The doctor gave her a hormonal drug to induce labor. Specify this drug:
After a patient had taken a blocking agent, his heart rate (HR) increased. Pressing on the eyeballs didn’t result in the expected reflectory decrease in heart rate. What exactly was blocked by the drug in the pacemaker cells?
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